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🩺 Composition & Therapeutic Class

  • Glimepiride (1 mg): A sulfonylurea class medication that stimulates the pancreas to release more insulin, helping lower blood sugar levels.

  • Metformin Hydrochloride (500 mg): A biguanide class medication that decreases the amount of glucose produced by the liver and increases the body's sensitivity to insulin.seluriapharma.com

This combination is used to manage Type 2 Diabetes Mellitus in adults whose blood glucose levels are inadequately controlled by diet and exercise alone or with other antidiabetic medications.


💊 Dosage & Administration

  • Typical Dosage: One tablet taken orally once daily, preferably with meals to minimize gastrointestinal discomfort.

  • Administration: Swallow the tablet whole with a glass of water. Do not crush or chew.

  • Missed Dose: If a dose is missed, take it as soon as you remember unless it's almost time for the next dose. Do not double doses to make up for a missed one.


⚠️ Precautions & Warnings

  • Kidney Function: Use with caution in patients with kidney impairment. Metformin is contraindicated in severe renal dysfunction due to the risk of lactic acidosis.

  • Liver Function: Monitor liver enzymes regularly, as both components can affect liver function.

  • Alcohol Consumption: Limit alcohol intake, as it can increase the risk of lactic acidosis.

  • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

  • Allergic Reactions: Rare allergic reactions may occur. Seek immediate medical attention if symptoms like swelling or rash appear.


💡 Lifestyle Recommendations

  • Diet: Follow a balanced, low-fat, high-fiber diet rich in fruits, vegetables, and whole grains.

  • Exercise: Engage in regular physical activity, aiming for at least 150 minutes of moderate-intensity exercise per week.

  • Monitoring: Regularly monitor blood glucose levels as advised by your healthcare provider.